You are managing a patient admitted with worsening heart failure symptoms. She has been diagnosed with idiopathic pulmonary arterial hypertension and receives continuous intravenous epoprostenol. An ECG shows atrial flutter with a rate of 110 bpm. Which of the following is true?

Choose any one
An interruption to the intravenous epoprostenol infusion can be tolerated for up to 6 hours
Atrial flutter with a high ventricular rate may explain the deterioration and should be treated urgently, if necessary with cardioversion
Treatment with epoprostenol is only for symptomatic relief
If leakage from the indwelling line is suspected, you should never switch to a peripheral line.